Resist the temptation to be drunk or on drugs during the tattoo session. Most artists simply won't work on someone who appears to be under the influence of such substances. And you want to be lucid to make sure you get the tattoo you really want.

Take over-the-counter anti-inflammatory medication or other pain relievers before you sit down in the chair. Also consider asking your tattooist whether she has any numbing or desensitizing gel available, which may cut down on the pain just a little bit.

During the tattoo procedure, breathe deeply and steadily to keep your heart rate under control and to avoid fainting. Try not to think about what the needle is doing—dragging and jack hammering through your skin—and distract yourself by talking to a friend, watching television, listening to music, or meditating.

If the pain becomes unbearable, ask the tattoo artist if you can take a break. A large tattoo can take hours to complete, and a good tattooist will understand if you need to step outside or rest periodically.

Once the tattoo is finished, the tattooist should cover it with a light film of plastic wrap or something similar. This typically stays on for less than 24 hours and does not offer any protection from pain. Continue to take over-the-counter pain medication as needed. Do not lean on, scratch or poke at the new tattoo. Do not apply any balms not suggested by your tattoo artist—some lotions can cause irritation or fade out the tattoo prematurely. Immediate redness and bruising is normal. Scabbing also may occur.